P 52: Interferon beta-a1 vs. Teriflunomide for Multiple Sclerosis

p 52: interferon beta-a1 vs. teriflunomide for multiple sclerosis

multiple sclerosis (ms) is an inflammatory disorder, in which neurons in central nervous system (cns) become demyelinated .ms is named for its formation of plaques due to sclerosis of myelin. variable degree of demyelination results in mild, mediate or severe symptomatic episodes of this disease. it is commonly characterized by recurrent relapses and often followed by severe neurological disabi...

Alemtuzumab vs. interferon beta-1a in early multiple sclerosis.

BACKGROUND Alemtuzumab, a humanized monoclonal antibody that targets CD52 on lymphocytes and monocytes, may be an effective treatment for early multiple sclerosis. METHODS In this phase 2, randomized, blinded trial involving previously untreated, early, relapsing-remitting multiple sclerosis, we assigned 334 patients with scores of 3.0 or less on the Expanded Disability Status Scale and a dis...

Teriflunomide for the treatment of multiple sclerosis.

Teriflunomide is a new active drug which has recently been approved as a first-line treatment of relapsing forms of MS in the US, Australia, Argentina, and the European Union. It is characterized by a once-daily oral application and a well-established long-term safety profile. The main therapeutic effect is considered to be mediated via the inhibition of the de novo synthesis of pyrimidine in p...

Interferon beta and suicide in multiple sclerosis.

Fingolimod versus High Dose Interferon Beta-1a in Multiple Sclerosis: A Randomized Clinical Trial

Background: High dose Interferon Beta and Fingolimod are efficient in Multiple Sclerosis. Objectives: Comparison the efficacy of these two drugs in patients with treatment failure on low dose interferon beta. Materials and Methods: The MS patients (McDonald criteria 2010) with the history of unbeneficial treatment on low dose interferon beta participated in this randomized clinical trial ...

Meningioma growth during interferon beta-1A treatment for multiple sclerosis.

Fleury Diagnostic Center, Section of Radiology, São Paulo SP, Brazil; Santa Casa de Misericórdia de São Paulo, Section of Radiology, São Paulo SP Brazil; Santa Casa de Misericórdia de São Paulo, Section of Neurology, São Paulo SP, Brazil; Santa Casa de Misericórdia de São Paulo, Section of Neurosurgery, São Paulo SP, Brazil; Santa Casa de Misericórdia de São Paulo, Section of Pathology, São Pau...